Intercellular communication in cardiac muscle.
نویسندگان
چکیده
منابع مشابه
An Official Journal of the American Heart Association BRIEF REVIEWS Intercellular Communication in Cardiac Muscle
THE heart muscle was conceptualized as an anatomical syncytium for many years (Heidenhain, 1901; Godlewsky, 1902). With the development of electron microscopy, it was proved that cardiac fibers are composed of isolated cells separated by specialized zones—the so-called intercalated discs (Sjostrand and Andersson, 1954). The discs comprise three junctional specializations: (1) the macula adhaere...
متن کاملIntercellular communication in cultured human vascular smooth muscle cells.
Intercellular communication through gap junction channels plays a fundamental role in regulating vascular myocyte tone. We investigated gap junction channel expression and activity in myocytes from the physiologically distinct vasculature of the human internal mammary artery (IMA, conduit vessel) and saphenous vein (SV, capacitance vessel). Northern and Western blots documented the presence of ...
متن کاملAldosterone Disrupts the Intercellular Flow of Glucose in Cardiac Muscle
The activation of the renin-angiotensin system is known to impair intercellular communication in the heart, but the role of aldosterone on the process of chemical communication and particularly the intercellular diffusion of glucose between cardiomyocytes is not known. This problem was investigated in cell pairs isolated from the left ventricle of adult Wistar Kyoto rats. For this, fluorescent ...
متن کاملIntercellular Communication in Bacteria
Historically, conventional thinking in evolutionary biology has drawn a bright line separating multicellular from unicellular organisms. Only the cells of animals, plants, and fungi were thought capable of achieving the synchrony required to function as a collective. Bacteria, in contrast, were perceived as blind, deaf, and mute, with each cell single-mindedly focusing on its own metabolism and...
متن کاملIntercellular communication in atherosclerosis.
Cell-to-cell communication is a process necessary for physiological tissue homeostasis and appears often altered during disease. Gap junction channels, formed by connexins, allow the direct intercellular communication between adjacent cells. After a brief review of the pathophysiology of atherosclerosis, we will discuss the role of connexins throughout the different stages of the disease.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Research
سال: 1982
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.51.1.1